The term Dex refers to a special classification of existing weapons that have been modified and optimized by the Tenno. Dex versions of weapons are characterized by their purple-blue metallic finish with Lotus branding on the grip or stock of the weapon, modified stats such as increased accuracy, damage, and/or base critical strike chance in lieu of firing rate, and added polarities for expanded modding capability.

So far, Dex variants of weapons have only ever been offered on a limited-time availability basis coinciding WARFRAME's Anniversary of its release on PC.