See the user build section for builds using this weapon.
Use Cronus as a replacement to your Skana, it is easy to craft and is an overall damage boost.
Be careful if using against Infested. Though the high slash damage is effective against them, the fact that the Cronus only strikes one target at a time may make using the weapon inefficient against the hordes the Infested tend to come in.
Use straight damage mods like Pressure Point instead of charge damage mods like Killing Blow. Correctly modded, the Cronus's regular attacks can actually do more damage than its charged attacks.
The listed firing rate is a speed multiplier for longswords. The real rate is 2.2 hits per second (0.45s to hit once). This is because the firing and charge rate of melee weapons often gets skewed due to attack animations.
As of update 7.8 the Cronus Blueprint is only a guaranteed drop the first time Tolstoj is completed and the % chance for it to drop decreases each run afterward. This was put in place to prevent credit farming.