For effective use of non-hitscan weapons, it is strongly recommended to learn how to lead your target. In short, leading means aiming ahead of your target so the projectile still hits him. It can be a challenge to learn it, low level Grineer are recommended for practicing.
Despair daggers are affected by the mod Lethal Momentum, making it much easier to hit moving targets and longer range targets.
Currently, while holding a Datamass, there is no proper "animation" or "alignment" of the Despair, for running with the Datamass. The Despair will float above/outside of your Warframe's hands, as if you had a pistol in your hand instead. This problem also occurs when performing a Jump Kick.
Trails from the blades are much brighter with longer decay times since Update 11. This may be an intended effect.
A "monofilament" is a fictional type of wire, consisting of a single strand of strongly bound together molecules. This theoretically creates an edge that is micron or even nanometer thin, the sharpest possible.
Typically, they are applied as a cutting tool or a weapon that can sever nearly any object or other molecules.
Organic molecular wires have been proposed for usage in optoelectronics.
Similarly to the Hikou and Kunai, the Despair is a secondary thrown weapon that deals mostly Puncture damage.