An instrument of unrelenting harm.

The Lesion is an Infested polearm based off the Tipedo. Upon inflicting a Status Effect on its target, the Lesion gains bonuses to its Attack Speed and guaranteed Toxin b Toxin procs, which coupled with its primary focus on Slash b Slash damage makes it a dangerous weapon against lightly-armored targets.

This weapon can be sold for Credits646,000.

Manufacturing Requirements
Time: 12 hrs
Rush: Platinum64 45
MarketIcon Market Price: Platinum64 150 Blueprint2 Blueprints Price: Credits64 25,000

Characteristics Edit

This weapon deals primarily Slash b Slash damage.


  • Medium range attacks with a wide radius.
  • High Slash b Slash damage – effective against InfestedFlesh and Cloned Flesh enemies.
  • High status chance.
  • Stance slot has Zenurik Pol polarity, matches Shimmering Blight stance.
  • Comes with a Madurai Pol polarity.
  • Has an innate attack speed increase and bonus Toxin b Toxin damage upon landing a successful attack with a Status Effect.
  • Additional Toxin b Toxin damage added will combine with any single elements (or combined elements with Toxin b Toxin) on the weapon.


  • Low critical chance.
  • Low Puncture b Puncture damage – less effective against armor.
  • Shortest attack range of all polearms.
  • Very small slam attack radius.


  • On dealing Status Effects on an enemy, the Lesion has a unique feature whereby it gains 15% additional attack speed for 6 seconds, as well as 100% Toxin b Toxin damage.
    • This buff does not stack.
    • This buff duration is not refreshed upon inflicting procs while the buff is still active. The buff must first expire before another instance can be activated.
    • The Toxin b Toxin damage is additive to other elemental mods on the weapon.

Trivia Edit

  • Lesion is any abnormal damage or change in an organism's tissue, usually the result of injury or disease. It is derived from the Latin word laesio, which simply means "injury".
  • Though looking quite similar to the Tipedo (The Lesion's crafting component) in design and length, the Lesion uses Polearm stances while the Tipedo is a staff.
  • The Lesion has a non-static model; the "jaws" of the weapon close when not actively equipped, will open upon being wielded, and without a Stance equipped, the jaws will visibly "bite" on the thrusting second and fourth strikes of the combo.


  • Try building for status chance and attack speed to stack Slash b Slash andToxin b Toxin procs, which deal large amounts of DoT through shields.
  • Synergizes well with Saryn: her passive increases the duration of Status procs by 25% (adding to their total damage) and Toxic Lash guarantees procs along while adding even moreToxin b Toxin damage.

Lesion Skins


  • The Lesion, shown in the Update 18.5 Teaser
  • Inaros wielding a Lesion in the Update 18.5 Teaser
  • 18.5 Hub's Weapon Teaser
WeaponsDamageCompare AllCosmetics

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