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Nightmare Mode is an optional difficulty modifier introduced in Update 9.0. When Nightmare Mode is selected, up to two mission modifiers take effect that greatly increase the mission's difficulty, but completing the mission will reward players with Nightmare Mods, which positively affect two stats of a weapon, Warframe, or Companion.
To unlock Nightmare mode on a given planet, one must complete all mission nodes on that planet (barring Dark Sectors).
When Nightmare Mode is unlocked, the game randomly selects one mission node for Nightmare Mode from any planet every 8 hours, limiting the possible Nightmare missions (and thus, potential rewards) to 17 missions every 8 hours. If you already completed the Nightmare Mode mission for a given planet, a new mission node will be selected 8 hours after completion.
Mission nodes under the effects of Nightmare Mode have a scarlet background and a white swirl in lieu of a Faction icon. Mission modifiers will also be listed next to the mission type. From Update 11.0 onwards you may choose whether to run the mission in Nightmare Mode or not. If some of the players in given Cell do not have Nightmare Mode unlocked, only those with it unlocked should initiate the mission vote or else the mission will start normally.
A Nightmare Trial key, rather than the standard Trial key, is required to access the Nightmare Mode versions of The Law of Retribution and The Jordas Verdict. Additionally, random Nightmare Alerts may appear, special Alert Missions which guarantee a specific Nightmare Mod upon completing the mission. In exchange, the No Shields modifier is always among the selected modifiers.
All enemies encountered in Nightmare Mode have significantly increased levels, as well as massively increased damage and enemy spawns compared to their standard levels. Ciphers may not be used during Hacking and any summoned allied Specter will immediately be hostile to all players (except Shockwave MOAs spawned from a MOA Cabinet Spawner). Environmental Hazards can also appear as usual.
Up to two of the following challenges may occur per mission, and each modifier has an equal chance of being selected. Nightmare Trials do not use these modifiers, but instead change certain aspects of the Trial's stages to increase their difficulty appropriately:
Player and companion shields are reduced to zero.
Overshields cannot be created while this challenge is active, nor will any shield-affecting abilities work, including Valkyr's Paralysis.
This modifier is guaranteed to occur in Nightmare Alerts.
This modifier is ignored if the mission type is Hijack, even if it is an alert mission. No other modifier will take its place.
By virtue of having no shields, this modifier has no effect on Inaros and Nidus .
This modifier does not affect sentinels.
The mission has a 5-minute timer that will fail the mission if it runs down. Killing enemies will add 5 seconds to the timer.
Enemies dying from sources other than players (such as environmental hazards) will not contribute to the timer. Security Cameras and Corpus Turrets will contribute to the timer however.