“You're not supposed to be in here! You're going to ruin the surprise!”This article contains spoilers about the game's lore.
Patient Zero is a quest to search for Mutalist Alad V, introduced in Update 15.5, where players must find and locate Alad V's new Infested form to stop his plans of dominating the Origin System. Completing this quest will provide the blueprint necessary to create a Mutalist Alad V Assassinate Key, which is required to access the Mutalist Alad V Assassination mission that drops components for the Mesa Warframe.
In order for the player to start this quest, you must complete the Eris junction on Pluto. Upon completion, the player will be awarded with the Patient Zero Quest.
Go to the Quest section of the Codex, select the quest, then click "Begin Quest" to start.
Upon starting the quest, the players will receive an inbox message from Alad V himself, heavily infected by the Infestation, announcing the now-evolved Infested species (which he calls its empire). The transmission reads as follows:
Upon hearing the news, the Lotus immediately sends the Tenno to a Corpus Ship on Naeglar, Eris to extract data that would reveal what the Corpus know about Alad V, playing out as a Spy mission. The Corpus had been searching for Alad V for months due to his devastating attacks on their ships. Once the second datamass has been collected, Alad V contacts the player about appreciating his "gift" to them, signaling the arrival of Infested units on board the ship that will fight both Tenno and Corpus alike. The mission ends once all the Datamasses have been brought to extraction.
The data collected from the Corpus reveals that Alad V has gotten hold of another Warframe, with plans to infect it.
In order to triangulate Alad V's location, the Lotus sends the Tenno to sabotage three Infested Ships, with the first ship being located on Brugia, Eris. Once again Alad V contacts the player during the mission, telling them of his plans for evolution and further spreading the Infestation. Lotus comments that the Infestation is changing Alad V's mind, making him think like an Infested.
The Hive Sabotage mission takes place on Saxis, Eris. Here, Alad V expresses his admiration for his Mutalists, and details his plans on making a Mutalist Warframe. At the end of the mission, a nervous Ordis asks whether it is possible for a Warframe to be infested.
The third and final Hive Sabotage mission is set on Kala-azar, Eris. Alad V now expresses his complete disregard of Corpus philosophy by denouncing the ideals of profit. At the conclusion of the mission, the Lotus finally finishes tracking down the location of Alad V's laboratory.
At this point, Lotus, referring to how Alad V seems to have changed, remarks that the Infestation has gotten to his mind and that he is not using the Infested as a weapon, he is Infested.
With the laboratory's location uncovered, the Lotus sends in the Tenno to Xini, Eris, to destroy the lab, ensuring that Alad V cannot create any more Mutalist Infested even if he has already escaped from the area. Players are tasked with a Sabotage mission aboard a Corpus Ship to destroy its reactor core.
After the reactor core is destroyed, Alad V will send in an Infested Mesa against the player to show off his work. The Lotus immediately insists that the Mesa, was in fact "not a Tenno. That's a hollow Warframe being puppeted by Infested flesh. Put it out of its misery." The Infested Mesa uses her Regulator Pistols and a Plasma Sword as its weapons, and can parry player attacks. Players must kill the Infested Mesa before they can continue to extraction.
Completing the mission rewards the Mutalist Alad V Assassinate Key blueprint.
- Patient Zero is a medical science term commonly used for the initial patient in the investigation of a global epidemic or pandemic.
|Main Quests||Vor's Prize • Once Awake • The Archwing • Stolen Dreams • The New Strange • Natah • The Second Dream • The War Within • The Sacrifice|
|Side Quests||Howl of the Kubrow • A Man of Few Words|
|Warframe Quests|| Hidden Messages (Mirage) • The Limbo Theorem (Limbo) • Patient Zero (Mesa) |
The Jordas Precept (Atlas) • Sands of Inaros (Inaros) • The Silver Grove (Titania)
The Glast Gambit (Nidus) • Octavia's Anthem (Octavia) • Chains of Harrow (Harrow)