Powered by a bio-chemical reaction, the infested Synapse rifle fries its targets with a steady stream of electricity[sic].

The Synapse is an Infested bio-weapon similar to the Amprex that shoots a Corrosive b Corrosive stream. It is only available through Bio Lab Research in the Dojo.

The Synapse can be sold for Credits647,500.

Manufacturing Requirements
Time: 24 hrs
Rush: Platinum64 35
MarketIcon Market Price: Platinum64 N/A Blueprint2 Blueprints Price:Credits6450,000
Bio Lab Research ClanAffinity64 3,000
Time: 72 hrs
Prereq: Embolist
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This weapon deals Corrosive b Corrosive damage.


  • Innate Corrosive b Corrosive damage – effective against Ferrite Armor and Fossilized.
  • Highest critical chance of all continuous and automatic primaries.
  • Highest critical damage of all continuous primaries.
  • Decent status chance.
  • Deals 20% additional damage on headshots.
  • High reload speed.
  • Large magazine size.
  • Consumes 0.5 ammo per tick of damage.


  • Innate Corrosive b Corrosive damage – less effective against Proto Shields.
  • Damage ramps up from 20% to 100% over 0.6 seconds when firing. After firing stops for 0.8 seconds, the damage decays back to 20% over 2 seconds.
  • Limited range of 27 meters.

Weapon LoadoutsEdit

Main article: Category:Synapse Build

See the user build section for builds using this weapon.


  • It is a good weapon to use against Ferrite armor, especially combined with Volt's Electric Shield.
    • As of Update 11.0, the Synapse can no longer do constant red crits when used in conjunction with Volt's Electric Shield.
  • Compared to the very similar Amprex, the Synapse deals significantly more damage when fully modded, due to its innate corrosive damage allowing for the addition of other secondary elements. But does not have the property of the shots chaining to other enemies, making the Synapse better for single-target damage while the Amprex excels at crowd control.


  • Crafting the Synapse initially required 11 Mutagen Masses and 3 Forma before being announced as a mistake, reducing it down to 5 and 2 respectively.
  • The tendrils at the front end of the Synapse move, retracting and enclosing the muzzle upon holstering the rifle. This suggests the weapon is a living organism.
  • A Synapse is a nervous system structure that acts as a 'gate' between neurons, allowing electrical signals to be passed between nerve cells. Synapses help form the electrical pathways of the nervous system.
  • This weapon seems to be based on the Electric Crawler as it has similar lighting attacks.


  • Synapse Colour Customization


Patch HistoryEdit

Update 22.14
  • Fixed Beam weapons not being able to damage enemies (alive but in a ragdolled state) when being affected by certain ‘crowd control’ Abilities.
  • Damage now ramps up over 0.6 seconds and after moving off target there is a delay of 0.8 seconds before it starts to decay over 2 seconds.
  • All Beam weapons now start their Damage ramp up at 20% (instead of 10%).
  • The Multishot chance should now apply more consistently with Beam weapons.
  • Fixed Beam weapons continuously firing when quick Meleeing.
  • Increased Range from 20m to 27m.
  • Increased Damage from 18 to 20.

Hotfix 22.13.4

  • Increased the Beam weapon Damage ramp up time from 0.8 to 1 second.
  • Fixed Beam weapon Damage ramp up not happening per target.

Hotfix 22.13.3

  • Perfect accuracy and high fire rate is balanced by limited range and damage ramping up from 10% to 100% over 0.8 seconds when firing and decays back to 10% over 1 second after stopping.
  • Mastery Rank increased from 6 to 11
  • Damage type changed from Electricity to Corrosive
  • Damage increased from 12.5 Corrosive per sec 18 Corrosive per tick
  • Fire Rate increased from 10 to 12
  • Status Chance increased from 10% per sec to 13% per tick of damage
  • Critical Chance decreased from 50% to 39%
  • Critical Damage increased from 2.0x to 2.7x
  • Range increased from 18m to 20m
  • Magazine size decreased from 100 to 70
  • Max ammo increased from 540 to 560
  • Ammo consumption decreased from 1.0 to 0.5 per tick of damag
  • Added innate 20% damage on headshots
  • Aimed Zoom reduced from 2.23x to 1.5x

See AlsoEdit

WeaponsDamageCompare AllCosmetics

WeaponsDamageCompare AllCosmetics

Start a Discussion Discussions about Synapse

  • Synapse vs Soma

    13 messages
    • wrote:I would say they are equally efficient but different in niches.  If you need from mid to long range LMG - take soma. If ...
    • crit multi shot synap...
  • What is a good end game weapon?

    79 messages
    • wrote:*cough* Twin Hek...*cough* That seems like an akward situation, those things are huge. Twin Mareloks would be a wic...
    • wrote: wrote: Penta absolutely outdamages every other AoE weapon and oneshots nearly everything lower than lvl ...