Powered by a bio-chemical reaction, the infested Synapse rifle fries its targets with a steady stream of electricity.

The Synapse is an Infested bio-weapon that projects constant arcs of electricity. It is only available through Bio Lab Research in the Dojo.

The Synapse can be sold for Credits647,500.

Manufacturing Requirements
Time: 24 hrs
Rush: Platinum64 35
MarketIcon Market Price: N/A Blueprint2 Blueprints Price: Credits6450,000
Bio Lab Research •ClanAffinity643,000
Time: 72 hrs
Prereq: Embolist
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This weapon deals Electricity b Electricity damage.



  • Reliant on its high critical damage potential, which makes it ill-suited against Object-based health.
  • Damage cannot be increased with Slash b Slash, Impact b Impact or Puncture b Puncture mods.
  • When combining elements, Electricity b Electricity damage is added last.
  • Limited range (18m).
  • Imperfect accuracy is worsened through Electric Shield.
  • Poor ammo efficiency.

Weapon LoadoutsEdit

Main article: Category:Synapse Build

See the user build section for builds using this weapon.


  • It is a good weapon to use against robotics, especially combined with Volt's Electric Shield.
  • With max Point Strike Synapse's crit chance can be increased up to 125%, ensuring critical hits while having 25% to proc Orange Critical Hits, though a Rank 3 Point Strike will be sufficient to increase its crit chance to 100% if low on mod energy.
  • As mentioned above, using the Synapse in conjunction with Volt's Electric Shield worsens the Synapse's imperfect accuracy. When using Heavy Caliber, the accuracy is somewhat low at even medium range.
    • As of Update 11.0, the Synapse can no longer do constant red crits when used in conjunction with Volt's Electric Shield.
  • Compared to the very similar Amprex, the Synapse deals significantly more damage when fully modded, but does not have the property of the shots chaining to other enemies, making the Synapse better for single-target damage while the Amprex excels at crowd control.


  • Crafting the Synapse initially required 11 Mutagen Masses and 3 Forma before being announced as a mistake, reducing it down to 5 and 2 respectively.
  • The tendrils at the front end of the Synapse move, retracting and enclosing the muzzle upon holstering the rifle. This suggests the weapon is a living organism.
  • A Synapse is a nervous system structure that acts as a 'gate' between neurons, allowing electrical signals to be passed between nerve cells. Synapses help form the electrical pathways of the nervous system.
  • This weapon seems to be based on the Electric Crawler as it has similar lighting attacks.
  • To have an elemental combination not including Electricity b Electricity, you previously had to add Stormbringer and/or High Voltage as a placeholder. As of a recent patch innate elements are placed last in the elemental combination hierarchy allowing better elemental versatility.


  • Synapse Colour Customization


Patch HistoryEdit

See AlsoEdit

WeaponsDamageCompare AllCosmetics

WeaponsDamageCompare AllCosmetics

Start a Discussion Discussions about Synapse

  • Synapse vs Soma

    13 messages
    • wrote:I would say they are equally efficient but different in niches.  If you need from mid to long range LMG - take soma. If ...
    • crit multi shot synap...
  • What is a good end game weapon?

    79 messages
    • wrote:*cough* Twin Hek...*cough* That seems like an akward situation, those things are huge. Twin Mareloks would be a wic...
    • wrote: wrote: Penta absolutely outdamages every other AoE weapon and oneshots nearly everything lower than lvl ...

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